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Thus, while identifying ferroptosis as an aspect of the macrophage in CD, much remains to be done to understand the physiological and pathophysiological implications of death pathways in myeloid cells

Sep 1 2018;33(9):1749-1756

There is extensive crosstalk between these cell death mechanisms, mainly through processes involving mitochondria, glutathione and the cystine transporter SLC7A11

Further, oxidative stress has been proven to facilitate the accumulation of strands of amyloid-beta proteins, normally present in the brain, to form amyloid plaques, which have classically been considered to be the cause and thus, the treatment target of Alzheimers disease

Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia

MicroRNA genes are transcribed by RNA polymerase II