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Yet, in an unrandomized and unblinded trial in patients with multiple myeloma, the administration of SRT501 was associated with a number of serious adverse effects, including kidney failure, such that the trial was halted (77)

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The pellet was resuspended in 800 l 0.2 M sulphuric acid and incubated on a roller for 2 h at 4C, followed by centrifugation for 10 min at 11,000 g to remove cellular debris

Bushman, A.J

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