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The original "Sad Affleck" meme (not to be confused with the smoking format) refers to the look of dismay worn by Affleck during a Batman v Superman press interview in 2016, which went viral paired with Simon & Garfunkel's "The Sound of Silence." The two memes have always been linked in the public consciousness different moments, same essential emotional frequency

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Despite these unfortunate findings, The encouraging news is that once you stop smoking, the majority of DNA methylation signals return to never-smoker levels after five years, says Roby Joehanes of Harvard Medical School and lead author on this study

But theres evidence that even short-term vaping can cause issues with lung function