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FEBS Lett 408(3):281284 Dinescu A, Brown TR, Barelier S, Cundari TR, Anderson ME (2010) The role of the glycine triad in human glutathione synthetase

A total of 18 distinct conserved motifs were identified (Figure 4B and Supplementary Figure 1)

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Interestingly, synthetic peptides appeared to suffer from solubility and modification, while the QconCAT peptide showed variability in digestion and required extensive digestion optimization Citation[229]

Together, these data position histone acetylation as a dynamic regulator of stress adaptation and antidepressant responsiveness across multiple brain circuits

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