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Diagnosis is made radiographically with joint space narrowing seen in the DIP and PIP joints of the fingers

Strong detergent sclerosants therefore have a low safety margin

Draw 1.0 mL of bacteriostatic water along the vial wall, swirl gently (do not shake), and store at 28 C protected from light

Credit: Trish Matheny Our testers love the ergonomics of the chug cap that securely fastens to the metal handle so it's out of the way when you're drinking from the silicone mouth piece

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Studies have shown that thiamine deficiency, and the resulting cognitive function decline, are the underlying factors in some neurodegenerative diseases (Alzheimers disease, Parkinsons disease)