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203 Similarly, in colorectal and pancreatic cancers, blockade of Hedgehog signaling has been shown to increase Wnt activity, facilitating CSC maintenance and therapeutic resistance

Acarbose belongs to a class of drugs called alpha-glucosidase inhibitors, commonly referred to as starch blockers. These drugs lower glucose by blocking breakdown of starches and slowing absorption of sugar and carbohydrates (ADA 2015d)

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This study demonstrates that macropinocytosis mediates chemotherapy and radiation resistance in cancer cells

The main limitation is that refrigerated storage does not fully halt degradation