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In its early stages, neurotrophic factors secreted by activated RMCs can protect the retina by alleviating retinal edema and protecting optic ganglion cells ( 2 Distribution and function of RMCs in the retina The RMCs account for approximately 90% of retinal glial cells and run through the whole layer of the retina (Subirada et al., 2018)

This conclusion supports an additional, most recent study demonstrating that BPC 157 exerts a significant protective effect against distant organ damage in the liver, kidneys, and lungs following lower extremity ischemia-reperfusion injury in rats [256]

FIGURE 8 Cardiolipin migrates to the outer membrane when it becomes oxidized, and it may ameliorate oxidative stress there through prior deuterium doping