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The process is highly tolerant of polypeptide length as similar isolated yields were obtained for the production of medium to large cyclic peptides (30-93 amino acids, ~2737% overall yields)

While statin therapy may not necessary lead to a reduction in circulating coenzyme Q 10 concentrations, further research needs to examine whether secondary coenzyme Q 10 deficiency might be predisposing patients to statin-induced myalgia (30)