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In individuals with overweight or obesity, treatment with semaglutide was associated with significant reductions in bodyweight, with a mean placebo-subtracted weight loss of 12.4% relative to placebo after 68 weeks reported in the STEP 1 trial

Zhong Y, Huang Y, Santoso MB, Wu LD

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With the exception of the phase II study of the anti-HGF antibody rilotumumab in gastric cancer, all trials demonstrated no relationship between MET expression and response to MET inhibitors [100]