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While preliminary studies are promising, further human research is needed to confirm these mechanisms

As of September 2023 it is on the FDA's Category 2 list of bulk drug substances that may not be compounded due to significant safety risks, and the agency has scheduled a Pharmacy Compounding Advisory Committee (PCAC) review for July 2026 covering proposed uses in opioid withdrawal, chronic insomnia, and narcolepsy

Yamazaki et al., 2019

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Each component can be dosed independently in research settings, and new combinations can be created without engineering entirely new molecules

Journal of the American Dietetic Association, 94 (1), 7177