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People with RA may have insulin resistance from ongoing inflammation, and GLP-1 drugs can address both

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This matters most for growth-hormone-axis peptides (CJC-1295, sermorelin, tesamorelin)

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The peptide shows particular activity in musculoskeletal tissue models, where it modulates growth hormone receptor expression in fibroblast cultures

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This typically represents increased activity in healing tissues rather than worsening of the condition

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