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11: 538-546 and updated in J Feline Med Surg 2013

Separately, various candidate MoAs of AXA-1125 were mechanistically represented in NAFLDsym, including the secretion of incretins (GLP-1 and GIP) and relevant downstream effects, direct reduction of oxidative stress, increased AMPK-responsive enzyme expression, inhibition of hepatic stellate cell activation and proliferation, and decreased TNF production

The negative attitude of Novo Nordisk was summed up by Lars Srenson, the company's CEO, who in 2005 argued 'Obesity is primarily a social and cultural problem