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Preclinical studies showed the ability of ImmTOR to mitigate immunogenicity of pegadricase resulting in sustained control of sUA in uricase-deficient mice 9

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The salts and derivatives of carnosine are also useful additions to the present invention and salts and derivatives thereof, which function as a pH buffer and also act as an agent of inhibiting protein cross-linking

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AM and JF conducted the experiments

The mobile phase was methanol and 0.1% phosphoric acid (9:1), the flow rate was 0.8 ml/min, the injection volume was 10 l, and the column temperature was 30 C